tag:blogger.com,1999:blog-26666124.post115843238440989470..comments2024-03-18T03:28:36.581-04:00Comments on Shrink Rap: SSRI Antidepressants & ViolenceUnknownnoreply@blogger.comBlogger15125tag:blogger.com,1999:blog-26666124.post-4544863799201536262012-02-08T12:43:51.721-05:002012-02-08T12:43:51.721-05:00Right. Multi-variable, difficult to correlate. ht...Right. Multi-variable, difficult to correlate. http://news.yahoo.com/mo-teen-gets-life-possible-parole-killing-141938731.htmlAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-26666124.post-76355079866481423962011-05-17T12:10:00.344-04:002011-05-17T12:10:00.344-04:00SSRI stands for selective serotonin re-uptake inhi...SSRI stands for selective serotonin re-uptake inhibitor. That means that it makes neurotransmitters released into the space between neurons hang out in that space longer - normally the neuron that released the neurotransmitters into that space will absorb the neurotransmitters that are not immediately absorbed by the neuron on the other side of the space between them (the space between them is called 'the synapse' of them). When the originating neuron absorbs the neurotransmitters that are not immediately absorbed by the neuron on the other side of the space between them it is called 're-uptake'. By calling a drug an SSRI the manufacturer says it inhibits the re-uptake of serotonin neurotransmitters. <br /><br />Excessive serotonin in the brain causes serotonin syndrome, a medically recognized syndrome in which too much serotonin in the body causes one or a number of physical and/or mental syndromes including nausea, palpitations, agitation and hallucinations. The body will make serotonin from tryptophan, a substance found in protein, pretty much as long as it has a supply of it; so the body uses an enzyme to control serotonin levels - monoamine oxidase breaks down serotonin. But it only breaks down the serotonin it comes into contact with through diffusion in synapses. The longer a serotonin molecule spends in the synapse the greater the probability it will be destroyed by encountering a monoamine oxidase molecule. So the re-uptake of serotonin actually conserves serotonin - we can conclude from this that selective serotonin re-uptake inhibitors make the brain burn through its serotonin supply faster than normal, eventually causing depletion.<br /><br />It is known that low serotonin levels are linked to hostility:<br /><br />http://www.dana.org/news/brainwork/detail.aspx?id=13182: "Now, researchers at Cambridge University and UCLA have found that serotonin also plays a critical role in regulating emotions such as impulsive aggression during social decision making. Impulsive aggression is the tendency to respond with hostility or aggression when faced with serious frustration.<br /><br />The researchers believe their results suggest that serotonin plays a critical role in social decision making by normally keeping aggressive social responses in check.<br /><br />By manipulating diet, the researchers were able to lower serotonin levels in the brains of healthy volunteers. Tryptophan, the essential amino acid necessary for the body to produce serotonin, can be obtained only through diet. Twenty healthy volunteers fasted overnight and were then given a protein drink, receiving drinks with tryptophan one day and without it the next.<br /><br />On both days, the study participants played the “Ultimatum Game,” in which one player poses a way to split a sum of money with a partner. If the partner accepts the offer, both players are paid accordingly. If the offer is rejected, however, neither player is paid. Some of the offers were considered “fair” (45 percent of the cash), while others were considered “unfair” (18 percent of the cash). When the players’ serotonin levels were low they showed increased aggression toward the offers they perceived to be unfair.<br /><br />The findings highlight why some people become aggressive or act impulsively when they have not eaten, says lead researcher Molly Crockett of the University of Cambridge Behavioral and Clinical Neuroscience Institute."<br /><br />http://www.time.com/time/magazine/article/0,9171,980153-1,00.html: "What, you may ask, is impulsivity? The standard answer tends to involve people who can't control their emotions or who get into bar fights. A study conducted in Finland found that men so characterized tend to be deficient in the brain hormone serotonin -- one of several chemical messengers that transmit signals between nerve cells."Gentlequantahttps://www.blogger.com/profile/06088974627534771194noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-25112967226926391612010-06-19T18:21:07.554-04:002010-06-19T18:21:07.554-04:00I can only tell you the truth about my son(shane c...I can only tell you the truth about my son(shane clancy) who was on cipramil (celexa)for 3 weeks when he killed himself and another young man.I can honestly say he was the kindest and most well rounded person that you are ever likely to meet. He had no underlying issues and was loved by everyone.He was the last person in the world to do something like this!Please be careful if you are contemplating going on anti-depressants..because the drug companies will do anything to keep the adverse side effects from the public! If you think im just a sad mother trying to make some sense of this then read on...<br />http://www.hc-sc.gc.ca/dhp-mps/medeff/advisories-avis/prof/_2004/celexa_hpc-cps-eng.php<br />Lundbeck (the makers of cipramil) already knew that their drug could cause self harm and harm to others.<br />Pity myself and Shane didn,t.<br />Leonie FennellLeoniehttps://www.blogger.com/profile/00102823677140890477noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-66901585669909802732010-03-08T22:54:46.761-05:002010-03-08T22:54:46.761-05:00I kicked a hole in the wall and choked my dad my 1...I kicked a hole in the wall and choked my dad my 1st day on effexor. I'm normally very mellow so it was very obvious what the problem was. Never took it again and never had that problem. I think it should be withdrawn from the market.mattnoreply@blogger.comtag:blogger.com,1999:blog-26666124.post-44006646004808016182010-02-20T17:28:15.652-05:002010-02-20T17:28:15.652-05:00I think that SSRI's, especially newer ones und...I think that SSRI's, especially newer ones under patent, are prescribed when older, less expensive drugs would be more appropriate. There is too much drug company influence upon medical schools and medical associations that set guidelines for doctors. <br /><br />Interestingly, Dr. Amy Bishop published this research about SSRI's causing nerve cell damage about the time the efforts to deny her tenure began last year.<br /><br /><br />http://www.dovepress.com/effects-of-selective-serotonin-reuptake-inhibitors-on-motor-neuron-sur-peer-reviewed-article-IJGMAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-26666124.post-8641593504558150332008-11-09T01:17:00.000-05:002008-11-09T01:17:00.000-05:00FWIW --I might suggest that in some cases, the mor...FWIW --<BR/><BR/>I might suggest that in some cases, the more outre side effects of SSRIs are not reported because the person taking the drug is afraid of being thought insane.<BR/><BR/>I had unbelievable rage while I was taking Effexor, and never told anyone about it because I was afraid of not being believed, and also afraid that there was something else seriously wrong with me. I am a highly intelligent and naturally moral person, and never hurt anyone despite my desire to do so, though I did put my fist through a wall at one point. But I had extremely disturbing violent impulses while on the drug, including a desire to maim or kill my beloved cats, and a strong desire to physically assault the woman I was dating at the time.<BR/><BR/>All of this vanished completely when I decided to voluntarily go off the drugs, which I had been told I would need for the rest of my life. As it happened, the psychoemotional disorder I had was consistently missed by therapists and clinicians, and SSRI drugs were not an appropriate treatment. This may or may not account for the peculiar side effects, but at any rate -- my thought is that possibly these things go unreported due to shame and fear on the part of the patient.David Rochesterhttps://www.blogger.com/profile/07084315223515340046noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-26043075260371134992008-10-28T17:40:00.000-04:002008-10-28T17:40:00.000-04:00Please forgive my horrible spelling and bad typing...Please forgive my horrible spelling and bad typing skills. Im actually going to college for this now.<BR/>I dont know if this will help anyone but I was recently taking paxil for anxiety.I was on 20mgs once a day. At first it made me a bit drowsey but the doctors made sure to tell me i had to let it get into my system for the full affect. The first month of taking this drug I felt great. No aniety attacks at all and in fact i was even happy. There is no "high " or any thing like that. However, as the second and third months came around I became cold, emotionless, with no sex drive, no humor, no personality and i seemed like a robot to my then boyfriend.<BR/>I still functioned and did what I had to in life but started to feel down for no reason , almost like i had this hurt in my heart and i didnt even no why it was there. It was a familiar feeling, ive suffered from it my whole life, bu usualoly a good hug from some one will ake it go away. Any how, the worse this got the more withdrawn I became and the more moody I was as well. I started to argue with every one, and I didnt even no why I was arguing with them, and my reasons made absolutely no sense.<BR/>So I started drinking with it . after about 2 weeks of drinking with this medication i started to get nasty. Then one night I just blacked out on some one who didnt in a million years deserve it. I just snapped for no reason and probley would have even gotten physical if some one hadnt had yelled my name to snap me out of it.. It was like a rage had taken over me and coming out of it i scared my self and was very confused. This was not in my character at all. Evry one was angry with me and i felt even worse. So I decided to stop taking it. I slowly went back to normal mentaly and didnt feel any with drawl symptons except for my mind feelig like it was just empty. i had no thoughts.<BR/>So a few months went by and I began to get anxiety attacks again. Normaly In hot humid climate with no air flow sets them off but they are horrible to deal with. So with out every knowing, I started to take what was left of my script. Again the same exact things happened but every one thought I was just becoming a b_tch! I didnt want to tell them i was back on it and I really wanted to see if this medication really is what caused me to be so nasty. So we had friends over and being that im in college ,thats a fairly normal thing. So Im not much of a drinker and hadnt drank since that last black out. I drank again, and i ended up flipping on my bf at the time. i even slappe him in the face and didnt have any recollection of doing this. Well I can tell you that ruined 3 years and my relationship ended over it. That 6 months of paxil took a tull on every one in my life. I havent touched it since and im fine. i still have anxiety but not often any more.<BR/>So i then started dating a new guy. And he happened to have some form of depression and the doctors prescribed him paxil.. I tried to warn him but he said he owuld be fine.. he slowly started to become the same way i was. very numb and secluded and absolutely no sex drive.. He drank twice on it.. the fiorst time resulted inhim snapping and beating up my friend.. This time he is now in jail for being drunk and violent and on paxil.. This is totaly out of his character as well for 37 years old. He doesnt remember alot of what happened, but he does remember at one point he couldnt stop the violence during the rage. <BR/>So now he is losing almost 5 years of his life for taking paxil and drinking with it.. He also admitted that as the months past, he 2 began to feel depressed like he had never felt in his life. to the point he questioned why he was even alive and didnt want to wake up.. I wasnt to that point but medication effects every one differently..<BR/>So please, if you are told not to drink with a medication, dont!! Theres a reason for it and your not a doctor!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-26666124.post-78229329756827414962007-08-25T11:14:00.000-04:002007-08-25T11:14:00.000-04:00Lifetime of antidepressants: diabetics need insuli...Lifetime of antidepressants: diabetics need insulin their whole lives; ppl with thyroid disorders have to take their thyroid meds for a lifetime. same same same, no shame.simonhttps://www.blogger.com/profile/06104937787480199190noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-79182473960575810912007-05-23T21:37:00.000-04:002007-05-23T21:37:00.000-04:00For a list of 1,650 criminal acts involving SSRIs ...For a list of 1,650 criminal acts involving SSRIs which have appeared in the media, go to www.ssristories.com<BR/><BR/>By going into the Index, you can read the actual media articles.<BR/><BR/>Psychiatrists have not picked up on the harm that antidepressants are doing to their patients because the patients never tell them. The patients go to their psychiatrist and say they are feeling great, just fine or something along these lines and then they are going home and acting in a crazy manner. Some kind of study really needs to be done on the bizarre behavior these people exhibit once they are on their SSRI. It is a National Tragedy.ssristorieshttps://www.blogger.com/profile/17842756789553472877noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-58910535654423356752007-05-09T01:35:00.000-04:002007-05-09T01:35:00.000-04:00It's really very simple... Eli Lilly knew about Pr...It's really very simple... Eli Lilly knew about Prozac Induced Suicidality, Mania and psychosis before the drug came on the market... Here is legal testimony on this subject:<BR/>http://www.baumhedlundlaw.com/<BR/>media/timeline.html<BR/><BR/>and...<BR/><BR/>"Suicidality, violence and mania caused by selective serotonin reuptake inhibitors (SSRIs): A review and analysis" <BR/>Peter R. Breggin MD <BR/>http://www.breggin.com/31-49.pdf"<BR/><BR/>School Shootings & Antidepressants" - Fox News <BR/>http://www.youtube.com/watch?v=Ifbjy-YKgRI<BR/><BR/>not to mention that...<BR/><BR/>Approximately half of all Americans have genetic defects that affect how they process these drugs."<BR/>http://www.healthanddna.com:80/<BR/>labelmesaneorderformdetail.htm<BR/><BR/>Add insult to injury... Prozac, et al, is no more effective than placebo and infinitely more dangerous/lethal... There should be no question as to the role these drugs play in current and regular violence.<BR/><BR/>"'I do not think I could explain to the BGA, a judge, to a reporter or even to my family why we would do this especially on the sensitive issue of suicide and suicidal ideation.’ — Memo from Bouchy C to L Thompson Re: Adverse Drug Event Reporting – Suicide Fluoxetine. November 13th 1990. Exhibit 117 in Forsyth vs Eli Lilly." - www.healyprozac.comSSRI-Researchhttps://www.blogger.com/profile/16303764165073458549noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-1159044256293811852006-09-23T16:44:00.000-04:002006-09-23T16:44:00.000-04:00I'm always curious about those links to side effec...I'm always curious about those links to side effects and whether people get the side effects because they read every word in the pharmacy handouts. I've had a lot of patients report the most bizarre side effects from whatever drugs, most of these side effects not painful or irritating in any way, and when I ask them, yes, they always read the little drug info sheet before they took the medicine. <BR/><BR/>I like it when you all contribute like that. :)Fat Doctorhttps://www.blogger.com/profile/09672076019531106668noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-1158956134783339182006-09-22T16:15:00.000-04:002006-09-22T16:15:00.000-04:00I don't know if suicidality is violence or not (I ...I don't know if suicidality is violence or not (I don't think of it as such, tho), but ever since starting Effexor XR, I went from not having been suicidal in many years, to frequent episodes, and alot of thinking about it, even when I wasn't sad or depressed.<BR/><BR/>Within the first month of starting it, and it's been that way ever since . . . from 0 to a ton. <BR/><BR/>Then again, I started therapy two-three months after, and I've been told, that as defenses start to come down, it's not uncommon that one actually gets worse, because the defenses you used to rely on are coming down. Alot of stressful life events since starting the med, too.<BR/><BR/>If all I said was, 0 before, to 1000% more after starting it, one would think the med was completely behind it. With the other things I said, though, that definitely changes things. I can't eliminate the possibility of a link, though, but it's complicated.Sarebearhttps://www.blogger.com/profile/09208596053319110470noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-1158946027461819872006-09-22T13:27:00.000-04:002006-09-22T13:27:00.000-04:00My appologies for my errors in typing. I seem to b...My appologies for my errors in typing. I seem to be having a hard time today.DrivingMissMollyhttps://www.blogger.com/profile/11476761316928942301noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-1158945881302218362006-09-22T13:24:00.000-04:002006-09-22T13:24:00.000-04:00As a PT I can say that during the very brief time ...As a PT I can say that during the very brief time I took Effexor, i noticed feelings of hostility and anger. Usually I tend to be suicidal and not homicidal so my abnormal thinking really got my attention.<BR/><BR/>At the time I was walking my dog and, as usual, I felt resentful of the many homeless people in the area of my expensive apartment.<BR/><BR/>However, beyond eing bothered, my thoughts extended to this; "I wish they were all dead. I bet I could kill them and get away with it because they're homeless and noone would care anyway."<BR/><BR/>Not Normal for me. Luckily, side effects from the Effexor enabled me to get off it.<BR/><BR/>Also, I will chime in about my little sister who took paroxetine ain junion high. This was before the black box warning. My mother told me that the medication caused her to lose it at school where she was provoking fights and being violent.<BR/><BR/>People are all so different. I was told I am very sensitive to medications.<BR/><BR/>The weirdest side effects I have had: Severe blurred vision from Effexor, breast tenderness from Zoloft, and upset stomach and diarhea from Cleocin (topical antibiotic for acne I could take one dose and be OK, but after that second dose, all bets were off).<BR/><BR/>LiltDrivingMissMollyhttps://www.blogger.com/profile/11476761316928942301noreply@blogger.comtag:blogger.com,1999:blog-26666124.post-1158907551917805632006-09-22T02:45:00.000-04:002006-09-22T02:45:00.000-04:00I like reading three perspectives at once!On a cou...I like reading three perspectives at once!<BR/><BR/>On a couple points, you've put into words, crystallized some half-formed thoughts I've had for awhile but hadn't really fleshed out.Sarebearhttps://www.blogger.com/profile/09208596053319110470noreply@blogger.com